Department Of Pharmacology
Pharmacology (Greek; pharmacon – drug, logos – study) It is the science dealing with study of all the aspects of drugs. Department of pharmacology is mainly concerned in rooting knowledge of drugs and research in undergraduate students. Department has well experienced and excellent faculties in teaching and research (preclinical and clinical). Adverse Drug Reaction Monitoring centre, under National Pharmacovigilance Programme of India (PvPI) is also functioning in the Department. Human and Animal ethics committees are the two pillars of our department in conducting various research activities for the faculties and students.
ACADEMICS
MBBS – Teaching the basic clinical application aspects of drugs as per CBME curriculum, importance of Ethics in research promoting good prescribing skills and GCP.
ACADEMICS
- Clinical and Experimental Pharmacology lab
- Analytical lab – Flame photometer, pH meter
- CNS lab – Facilities for Evaluation of Analgesics, Antidepressants, Antianxiety and Antiepileptic drugs
- Museum – Various scientists in Drug discovery, Drugs, Models and charts
- Departmental Library –Recent and advanced reading facilities & National and International Journals.
INSTITUTIONAL ANIMAL ETHICS COMMITTEE
Animal Ethics Committee (AECs) provides avenues for the students and faculty participation in the regulation of animal research.Institutional Animal Ethics Committee (IAEC) of GMC &ESI Hospital, Coimbatore is registered with ‘Committee for Control and Supervision of Experiments on Animals’ (CCSEA),Animal welfare division and Government of India for research and education purpose vide registration no. (1981/GO/Re/S/17/CPCSEA).
IAEC has been constituted to supervise and evaluate all aspects of the animal care and use program in holding and experiment on Animals (Control and Supervision) rules 1998; with a goal to perform scientific research involving experiments on animals ensuring ethical use of animals so that they are not subjected to unnecessary pain and sufferings.
OBJECTIVES
- To facilitate legitimate scientific research involving experiments on animals.
- Ensuring the ethical & minimal use of animals
- To ensure that animals are not subjected to unnecessary pain and suffering during experiments.
FUNCTIONS
The functions of IAEC are as follows:
- It approves research involving animals which confirm the various guidelines for use of animals in research.
- Reviews proposed use of animals in research and require any modifications necessary for approval or withhold approval prior to use ofanimals.
- Reviews and investigates legitimate concerns involving the care and use of animals during research.
- Reviews periodically the Institute’s animal facility.
- Ensures that all personnel involved in animal care and use are appropriately qualified to carry out the proposed activities.
APPLICATION FOR PERMISSION FOR ANIMAL EXPERIMENTS
| Form B | For the submission of research protocol |
| Form C | Record of animals bred/ acquired |
| Form D | Record of animals acquired and experiments performed |
COMPLETED RESEARCH PROJECTS
| S.No | Title of the study | Year of submission |
|---|---|---|
| Pre-Clinical Study on The Anti-Anxiety Effect of Carvedilol | 2017 | |
| 1. | Evaluation of analgesic effect of promethazine in rats | 2017 |
| 2. | Pre-Clinical Study on The Anti-Anxiety Effect of Carvedilol | 2017 |
| 3. | Evaluation of analgesics activity of aqueous extract ofcinnamomumzeylanicum bark in Wister rats | 2017 |
| 4. | Evaluation Of Anxiolytic And Anti- Depressant Effect Of Aprepitant In Adult Albino Mice | 2021 |
| 5. | Evaluation Of Analgesic Effect Of Fosinopril In Adult Albino Mice | 2021 |
PHARMACOVIGILANCE
Pharmacovigilance is the science where the activities are related to the detection, assessment, understanding and prevention of adverse effects or any other drug related problems. The information generated by Pharmacovigilance is useful in educating health care professionals about adverse drug reactions (ADR) and in the official regulations of drug use so as to reduce the risk of drug related harm to the patients.
The Pharmacovigilance Committee of our College is actively involved in the National Pharmacovigilance Programme of India. Activities involved in Pharmacovigilance are collection, communication and dissemination of ADR data linking with the Clinicians to provide expertise for assessing causality and severity of ADRs by using Naranjo algorithm and WHO scales.
The ADR data’s are entered in Suspected Adverse Drug reaction Reporting Form. Since we are ADR monitoring centre (AMC) according to Pharmacovigilance programme of India, our college Causality assessment committee will assess the causality and upload to Vigiflow for further action. This makes changes in the labelling of medicines indicating restrictions in use or statuary warnings, precautions or even withdrawal of the drug by the regulatory decision making authority.
| S.No | Title of the Journal |
|---|---|
| 1 | Evaluation of analgesic effect of Levofloxacin in adult albino rat. |
| 2 | A questionnaire based study on Knowledge, Attitude and Practice of ADR reporting and Pharmacovigilance among Health care workers in a tertiary care center |
| 3 | Evaluation of Antidepressant effect of aqueous extract of aegle marmelos leaves in adult albino mice. |
| 4 | OHA and BMD –Are they related |
| 5 | Prescription pattern of drugs for osteoarthritis in a tertiary care hospital |
| 6 | Open labelled randomized prospective study comparing the efficacy and safety of doxofylline and theophylline in COPD patients |
| 7 | Impact of mobile phone on sleep patterns in medical students. |
| 8 | “Pharmacology and Medical student perspectives” in a government tertiary care centre |
| 9 | Cost Minimization Analysis Of Antimalarials In India |
| 10 | A cross sectional study of learning style preference among 2nd year medical graduates using modified VARK questionnaire based on new curriculum. |
| 11 | Effect of bromocriptine quick release on serum lipid levels in Type 2 diabetes metilltus patients – An open label randomized controlled study |
| 12 | Evaluation of Antinociceptive activity of minocycline in Swiss albino mice |
| 13 | Assessment of factors influencing medication adherence among breast cancer patients |
ON GOING REASEARCH PROJECT
S.No Title of the Journal
1 Knowledge,attitude andpractice towardsartifical intelligence among healthcare workers and MBBS students in a tertiary care centre
2 Assessment of the level of knowledge,awareness and attitude towards “Basic life support” and “cardiopulmonary resuscitation “ among medical students,interns and medical post graduates of a medical college hospital.
3 Assessment of the level of knowledge,awareness and attitude towards BLS and CPR among general population of south Indian Metropolitan City.
4 Impact of mobile phones on physical and mental wellbeing of medical students in coimbatore
5 National exit test (next) and undergraduate medical students – merits”
6 Cross sectional study to estimate the quality of life and its predictors among type 2 diabetes patients and hypertensive patients in a tertiary care hospital
7 Impact of competency based medical education among students of government medical college and esic hospital, coimbatore
8 Depression in patients with chronic illnesses in a tertiary care hospital
9 Evaluation of sleep in hospitalized patients using pittsburgh sleep quality index
10 The impact of social media on the study habits of medical students
11 Impact of screen time among smart phone users using critical flicker fusion apparatus
12 Repercussion of mobile phone usage in youth- A questionnaire study
13 Exploration of cosmetic utilization pattern and knowledge of cosmetovigilance among medical undergraduates
14 Ground reality of animal research in this age of artificial intelligence- A questionnaire based study
15 Utilization of technology for M-Learning among medical undergraduates.
16 Awareness of ethics in medical practice- A questionnaire study among healthcare fraternity.
17 Association between depression and medication adherence in type 2 diabetes patients